The main causes of lung cancer (and cancer in general) include carcinogens (such as those in tobacco smoke), ionizing radiation, and viral infection. This exposure causes cumulative changes to the DNA in the tissue lining the bronchi of the lungs (the bronchial epithelium). As more tissue becomes damaged, eventually a cancer develops.
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Risk factors for lung cancer include: Tobacco use. Smoking and chewing tobacco are related to developing lung cancer, as well as to cancer of the mouth and throat. Over 85% of lung cancers are related to smoking.2 More than half of the people who are newly diagnosed with lung cancer are former smokers. Smoking unfiltered, high-tar cigarettes may put you at a higher risk than smoking filtered or low-tar cigarettes, although this has not been proved. The risk of developing lung cancer increases: The longer you smoke and The more cigarettes you smoke each day.
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